The Role of the Hippocampus in Memory

  • Location: The hippocampus is situated in the front part of the temporal lobe on both sides of the brain.
  • Structure: It’s a three-layered cerebral cortex, distinct from the six-layered neocortex.
  • Function: The hippocampus is crucial for the formation of both semantic (factual knowledge) and episodic (personal experiences) memories.
    • Without a hippocampus, new memories of both types cannot be formed.
    • The case of HM illustrates this point: he could not form new episodic memories (e.g., not knowing who the president is) or semantic memories (e.g., not knowing the meaning of new words).

Memory Consolidation and Retrieval

  • Memory Storage: Once memories are formed, they are transferred from the hippocampus to the neocortex for storage.
  • Semantic Memory Retrieval: Semantic memories are stored directly in the neocortex and can be accessed without involving the hippocampus.
    • Damage to the neocortex can result in the loss of specific semantic memories (as seen in the case of Jill Bolte Taylor, who lost her math skills).
  • Episodic Memory Retrieval: Episodic memories are also stored in the neocortex but require the hippocampus for retrieval (reconsolidation).
    • This process of reconsolidation allows for potential changes in the memory each time it is retrieved.