Motor Neurons and Muscle Fibers

This lecture segment explains the connection between motor neurons and the different types of skeletal muscle fibers.

Key Points:

  • Different motor neurons innervate different types of muscle fibers.
  • There are three main types of motor neurons:
    • Slow motor neurons: Innervate slow muscle fibers for sustained contractions.
    • Fast fatigue-resistant motor neurons: Innervate fast muscle fibers that can use both oxygen and glycogen for contractions lasting around 30 minutes.
    • Fast fatigable motor neurons: Innervate fast muscle fibers reliant solely on glycogen, leading to fatigue in 3-5 minutes.

Motor Units:

  • A motor unit consists of a single motor neuron and all the muscle fibers it innervates.
  • The number of muscle fibers per motor unit varies:
    • Slow motor neurons innervate few muscle fibers.
    • Fast fatigue-resistant motor neurons innervate more muscle fibers.
    • Fast fatigable motor neurons innervate the most muscle fibers.

Impact on Movement and Disease:

  • Recruitment of different motor neuron types allows for smooth movements.
  • In diseases like polio, motor neuron death leads to muscle weakness because the denervated muscle fibers cannot function.
  • Post-polio syndrome might arise due to overworked remaining motor neurons struggling to compensate for lost ones. Orderly Recruitment