The Brain’s Structure and Connectivity

This lecture focused on the development of the brain’s connectivity between its major parts.

Key Points:

  • The telencephalon, initially two separate hemispheres, expands and covers the other brain regions.
  • In an adult brain, two important structures bridge these regions:
    • Corpus callosum: Connects the two hemispheres, enabling communication between them.
    • Internal capsules: Connect the telencephalon to the diencephalon. They carry crucial information, including motor information to the muscles.

Brain Connectivity:

  • Initially, the hemispheres are separate structures.

  • The corpus callosum develops later, allowing communication between the hemispheres.

  • The internal capsules connect the telencephalon (cerebral cortex) to the diencephalon. They carry information, including motor signals that control muscles on the opposite side of the body.

    • (not a mid sagittal cut, it is para sagittal cut) Brain Regions:
  • Spinal cord: Carries signals between the brain and the body.

  • Hindbrain: Includes the pons, medulla, and cerebellum. Involved in basic functions like breathing and heart rate.

  • Midbrain: Relays sensory and motor information.

  • Diencephalon: Contains structures like the thalamus, which relays sensory information to the cortex.

  • Telencephalon: Makes up the cerebrum, the largest part of the brain. The outer layer is the cerebral cortex, responsible for higher functions like thinking and memory.

Additional Notes:

  • The space in the center of the brain (ventricles) contains cerebrospinal fluid and is not brain tissue.
  • A midsagittal cut divides the brain in half along the midline.
  • A parasagittal cut is similar to a midsagittal cut but slightly off-center.
  • A horizontal cut divides the brain parallel to the ground.

Final Diagram:

The lecture concludes by introducing a simplified brain diagram that will be used throughout the course. This diagram shows the major brain regions and their connections via the corpus callosum and internal capsules.