Lecture Notes: Autonomic Nervous System Across the Lifespan

I. Beyond “Fight or Flight” and “Rest and Digest”

  • The lecture clarifies that sympathetic and parasympathetic activity isn’t always at extremes.
  • We typically exist in a dynamic balance between the two, with shifts based on immediate needs (e.g., encountering a threat vs. relaxing after a meal).

II. Sympathetic Dominance Across the Lifespan

  • An additional layer of complexity is the gradual shift towards sympathetic dominance throughout life.
  • Young children: More parasympathetically dominant, focusing on growth and nutrient absorption.
  • Older adults: More sympathetically dominant, potentially contributing to conditions like hypertension.

III. Factors Influencing Autonomic Tone

  • Physical activity: Highly trained aerobic athletes exhibit stronger parasympathetic dominance (e.g., lower resting heart rate).
  • Age: As we age, the natural shift towards sympathetic dominance may contribute to age-related health concerns like hypertension.

IV. Connection to Future Lecture

  • The lecture concludes by foreshadowing a future segment discussing drugs targeting the autonomic nervous system to manage conditions like hypertension.

V. Key Takeaways

  • The autonomic nervous system’s activity isn’t solely “fight or flight” or “rest and digest.”
  • balance exists between sympathetic and parasympathetic activity, shifting based on immediate needs and life stage.
  • Sympathetic dominance increases with age, potentially impacting health.