The Importance of the Motor Hierarchy:

  • The motor hierarchy is a crucial system for generating movement.
  • Damage anywhere in this hierarchy will result in movement deficits.

Limitations of the Motor Hierarchy:

  • The motor hierarchy alone cannot produce the refined movements we’re accustomed to.
  • Movements would be imprecise without additional modulation.

Modulation by the Cerebellum:

  • The cerebellum acts like an orchestral conductor, ensuring smooth coordination between muscles and joints.
  • It receives sensory input (muscle, skin) and motor intention signals.
  • It compares intention with actual movement and adjusts the motor hierarchy accordingly.
  • Cerebellar damage leads to ataxia:
    • Dysmetria: inaccurate distance control (overshooting the target)
    • Decomposition of movement: jerky motions instead of smooth flow

Modulation by the Basal Ganglia:

  • The basal ganglia influence a higher level of movement control compared to the cerebellum.
  • It focuses on action selection: deciding whether or not to initiate movement.
  • Our natural state is to not move, and the basal ganglia help overcome this inertia.
  • Basal ganglia dysfunction manifests differently:
    • Parkinson’s disease (poverty of movement): difficulty initiating and executing movements.
    • Hyperkinetic disorders (excess movement): involuntary movements like chorea or ballismus.
    • These conditions reflect an imbalance between initiating a chosen movement and suppressing others.

Conclusion:

  • The motor hierarchy provides the foundation for movement.
  • The cerebellum and basal ganglia modulate this system for smooth, coordinated actions and appropriate movement selection.

Further Exploration:

  • The lecture will delve deeper into motor neurons and muscle types in the next unit.